{"id":1087665,"date":"2024-06-08T17:10:50","date_gmt":"2024-06-08T16:10:50","guid":{"rendered":"https:\/\/biocoach.health\/2024\/06\/08\/resveratrol-longevity-supplement-with-potential\/"},"modified":"2024-06-08T17:25:21","modified_gmt":"2024-06-08T16:25:21","slug":"resveratrol-longevity-supplement-with-potential","status":"publish","type":"post","link":"https:\/\/biocoach.health\/en\/2024\/06\/08\/resveratrol-longevity-supplement-with-potential\/","title":{"rendered":"Resveratrol &#8211; Longevity supplement with potential"},"content":{"rendered":"\n<p><strong>Resveratrol is a polyphenolic compound found in various plants, including grapes, blueberries, raspberries and mulberries. In recent years, it has <strong>attracted a lot of attention<\/strong> due to its potential health benefits &#8211; particularly by reducing the risk of cardiovascular disease and extending lifespan in some organisms.<\/strong><\/p>\n\n<p><strong>Mechanisms of action<\/strong><br\/>The health benefits of resveratrol are attributed to its effectiveness in different biological pathways:<\/p>\n\n<ul class=\"wp-block-list\">\n<li>Oxidative stress: Resveratrol helps to reduce <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9086005\/#CR50\">oxidative stress<\/a> by scavenging free radicals and increasing the production of antioxidant enzymes that can protect cells from damage caused by reactive oxygen species (ROS).<\/li>\n\n\n\n<li>Inflammation: Resveratrol has been shown to inhibit the production of <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7796143\/#:~:text=Resveratrol%20exhibits%20anti%2Dinflammatory%20effects,production%20%5B6%2C98%5D.\">inflammatory mediators<\/a> such as cytokines and prostaglandins, which play a key role in the development of chronic diseases such as cardiovascular diseases, cancer and neurodegenerative disorders.<\/li>\n\n\n\n<li>Mitochondrial dysfunction: Resveratrol has been shown to improve <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S221345302300188X\">mitochondrial function<\/a> by increasing ATP production and reducing oxidative stress, which may help maintain cellular energy metabolism and prevent age-related diseases.<\/li>\n\n\n\n<li>Apoptosis: Resveratrol has been shown to induce <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28197625\/\">apoptosis<\/a> (programmed cell death) in cancer cells, which may help prevent tumor growth and progression.<\/li>\n\n\n\n<li>Promoting survival and <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9653554\/\">angiogenesis<\/a>: Resveratrol has been shown to promote cell and blood vessel survival, which may help maintain tissue health and prevent ischemic disease.<\/li>\n<\/ul>\n\n<p><strong>Health benefits<\/strong><br\/>Resveratrol has been shown to have potential health benefits for various diseases, including:<\/p>\n\n<ul class=\"wp-block-list\">\n<li>Cardiovascular diseases: Resveratrol has been shown to reduce the risk of cardiovascular disease by improving lipid profiles, lowering blood pressure and inhibiting platelet aggregation.<\/li>\n\n\n\n<li>Cancer: Resveratrol has been shown to have anti-cancer properties, including inhibiting tumor growth, inducing apoptosis and reducing metastasis.<\/li>\n\n\n\n<li>Eye diseases: Resveratrol has been shown to have potential therapeutic effects in age-related eye diseases such as glaucoma, cataracts, diabetic retinopathy and macular degeneration.<\/li>\n\n\n\n<li>Neurodegenerative disorders: Resveratrol has been shown to have neuroprotective effects, including reducing oxidative stress, inflammation and mitochondrial dysfunction, which may help prevent neurodegenerative diseases such as Alzheimer&#8217;s and Parkinson&#8217;s.<\/li>\n<\/ul>\n\n<p>However, despite its potential health benefits, resveratrol also has some limitations and disadvantages:<\/p>\n\n<ul class=\"wp-block-list\">\n<li>Bioavailability: Resveratrol has poor bioavailability, which means that only a small amount of the compound is absorbed into the bloodstream after ingestion. This may limit its effectiveness in humans.<\/li>\n\n\n\n<li>Toxicity: Some animal studies have shown that high doses of resveratrol can cause toxicity, including heart inflammation, kidney damage and death. This highlights the importance of investigating the potential toxicity of resveratrol in humans.<\/li>\n\n\n\n<li>Hormonal effect: The effect of resveratrol can be dose-dependent, with low doses generally having a positive effect and high doses having a toxic effect. This is known as the hormetic effect.<\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9086005\/#CR50\">Lack of<\/a> human <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9086005\/#CR50\">studies<\/a>: Although resveratrol has shown promise in animal studies, there is a lack of comprehensive, randomized clinical trials in humans to confirm its efficacy and safety in the treatment of various diseases.<\/li>\n<\/ul>\n\n<p><strong>Conclusion<\/strong><\/p>\n\n<p>In summary, resveratrol is a promising substance with <a href=\"https:\/\/nomix.ai\/2024\/05\/27\/interventions-for-slowing-stopping-or-reversing-aging-and-extending-healthspan\/\">potential health benefits<\/a> for a longevity lifestyle, but further research is needed to explore its limitations and drawbacks, particularly in terms of bioavailability, toxicity and efficacy in humans.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Resveratrol is a polyphenolic compound found in various plants, including grapes, blueberries, raspberries and mulberries. In recent years, it has attracted a lot of attention due to its potential health benefits &#8211; particularly by reducing the risk of cardiovascular disease and extending lifespan in some organisms. Mechanisms of actionThe health benefits of resveratrol are attributed [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1087660,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[97,125,66],"tags":[181,227,228,103,226,224,225],"class_list":["post-1087665","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-micronutrients","category-nutrition","category-uncategorized","tag-food-supplements","tag-grapes","tag-nad-en-2","tag-nmn-en","tag-red-wine","tag-resveratrol-en","tag-supplement-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Resveratrol - Longevity supplement with potential - BIOCOACH Longevity<\/title>\n<meta name=\"description\" content=\"Resveratrol - Longevity supplement with potential: reducing the risk of cardiovascular disease and prolonging healthspan\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/biocoach.health\/en\/2024\/06\/08\/resveratrol-longevity-supplement-with-potential\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Resveratrol - Longevity supplement with potential - BIOCOACH Longevity\" \/>\n<meta property=\"og:description\" content=\"Resveratrol - Longevity supplement with potential: reducing the risk of cardiovascular disease and prolonging healthspan\" \/>\n<meta property=\"og:url\" content=\"https:\/\/biocoach.health\/en\/2024\/06\/08\/resveratrol-longevity-supplement-with-potential\/\" \/>\n<meta property=\"og:site_name\" content=\"BIOCOACH Longevity\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/NOMIXAI\" \/>\n<meta property=\"article:published_time\" content=\"2024-06-08T16:10:50+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-06-08T16:25:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0240.png?fit=1024%2C1024&ssl=1\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"KMR\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@biocoachdapp\" \/>\n<meta name=\"twitter:site\" content=\"@biocoachapp\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"KMR\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/biocoach.health\/en\/2024\/06\/08\/resveratrol-longevity-supplement-with-potential\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/biocoach.health\/en\/2024\/06\/08\/resveratrol-longevity-supplement-with-potential\/\"},\"author\":{\"name\":\"KMR\",\"@id\":\"https:\/\/biocoach.health\/en\/#\/schema\/person\/b6b0bd6b8445602d5fc237d75716e526\"},\"headline\":\"Resveratrol &#8211; 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WirkungsmechanismenDie\u2026","rel":"","context":"In &quot;Ern\u00e4hrung&quot;","block_context":{"text":"Ern\u00e4hrung","link":"https:\/\/biocoach.health\/category\/ernaehrung\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0240.png?fit=1024%2C1024&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0240.png?fit=1024%2C1024&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0240.png?fit=1024%2C1024&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0240.png?fit=1024%2C1024&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":1087606,"url":"https:\/\/biocoach.health\/en\/2024\/06\/01\/astaxanthin-as-an-anti-ageing-factor\/","url_meta":{"origin":1087665,"position":1},"title":"Astaxanthin as an anti-ageing factor","author":"BIOCOACH","date":"June 1, 2024","format":false,"excerpt":"The carotenoid Astaxanthin, a member of the xanthophyll subclass, has numerous clinical benefits due to its unique effect on the cell membrane. It neutralizes free radicals and oxidants by absorbing or releasing electrons without becoming a pro-oxidant. Its linear structure and polar-nonpolar-polar arrangement allow it to fit precisely into cell\u2026","rel":"","context":"In &quot;Micronutrients&quot;","block_context":{"text":"Micronutrients","link":"https:\/\/biocoach.health\/en\/category\/micronutrients\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0144.png?fit=1024%2C1024&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0144.png?fit=1024%2C1024&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0144.png?fit=1024%2C1024&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0144.png?fit=1024%2C1024&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":1087742,"url":"https:\/\/biocoach.health\/2024\/06\/24\/alpha-ketoglutarat-akg-wirkt-positiv-auf-longevity\/","url_meta":{"origin":1087665,"position":2},"title":"Alpha-Ketoglutarat AKG wirkt positiv auf Longevity","author":"BIOCOACH","date":"June 24, 2024","format":false,"excerpt":"Alpha-Ketoglutarat (AKG) ist ein Molek\u00fcl, das eine entscheidende Rolle im Tricarbons\u00e4urezyklus (TCA-Zyklus) spielt, der auch als Krebszyklus oder Zitronens\u00e4urezyklus bekannt ist. Bei diesem Zyklus handelt es sich um eine Reihe von chemischen Reaktionen, die in den Zellen lebender Organismen ablaufen und N\u00e4hrstoffe in Energie umwandeln. Der TCA-Zyklus ist ein zentraler\u2026","rel":"","context":"In &quot;Ern\u00e4hrung&quot;","block_context":{"text":"Ern\u00e4hrung","link":"https:\/\/biocoach.health\/category\/ernaehrung\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0521.png?fit=1024%2C1024&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0521.png?fit=1024%2C1024&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0521.png?fit=1024%2C1024&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0521.png?fit=1024%2C1024&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":1087269,"url":"https:\/\/biocoach.health\/en\/2024\/05\/25\/longevity-lifestyle-ampk-sirtuine-mtor\/","url_meta":{"origin":1087665,"position":3},"title":"Longevity Lifestyle: AMPK, Sirtuine, mTOR","author":"KMR","date":"May 25, 2024","format":false,"excerpt":"Longevity research has identified three important signaling pathways in the body that slow down the aging process and promote health. They act as energy and nutrient sensors in the body and react to changes in our cells. Each actor has its own mechanism that regulates bodily functions and the ageing\u2026","rel":"","context":"In &quot;Micronutrients&quot;","block_context":{"text":"Micronutrients","link":"https:\/\/biocoach.health\/en\/category\/micronutrients\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/05\/IMG_0067.png?fit=1024%2C1024&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/05\/IMG_0067.png?fit=1024%2C1024&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/05\/IMG_0067.png?fit=1024%2C1024&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/05\/IMG_0067.png?fit=1024%2C1024&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":1088200,"url":"https:\/\/biocoach.health\/2024\/10\/28\/resveratrol-schlaegt-nicht-an-meta-analyse-zeigt-keinerlei-stoffwechsel-effekt\/","url_meta":{"origin":1087665,"position":4},"title":"Resveratrol schl\u00e4gt nicht an: Meta-Analyse zeigt keinerlei Stoffwechsel-Effekt","author":"KMR","date":"October 28, 2024","format":false,"excerpt":"Die Polyphenolverbindung Resveratrol wird seit etwa 20 Jahren als \"Anti-Aging\"-Therapie gehandelt, bisher allerdings ohne st\u00fctzende wissenschaftliche Erkenntnisse. K\u00fcrzlich wurden in einer systematischen Metaanalyse die Auswirkungen von Resveratrol auf die Stoffwechselgesundheit untersucht und keine signifikanten Vorteile im Vergleich zu Placebos festgestellt. Grunds\u00e4tzlich basiert die angenommene Wechselwirkung von Resveratrol und Stoffwechselgesundheit auf\u2026","rel":"","context":"In &quot;Ern\u00e4hrung&quot;","block_context":{"text":"Ern\u00e4hrung","link":"https:\/\/biocoach.health\/category\/ernaehrung\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/10\/IMG_1706.png?fit=1200%2C1200&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/10\/IMG_1706.png?fit=1200%2C1200&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/10\/IMG_1706.png?fit=1200%2C1200&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/10\/IMG_1706.png?fit=1200%2C1200&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/10\/IMG_1706.png?fit=1200%2C1200&ssl=1&resize=1050%2C600 3x"},"classes":[]},{"id":1087624,"url":"https:\/\/biocoach.health\/en\/2024\/06\/03\/the-anti-ageing-spice-turmeric\/","url_meta":{"origin":1087665,"position":5},"title":"The anti-ageing spice turmeric","author":"KMR","date":"June 3, 2024","format":false,"excerpt":"Curcumin is a compound found in turmeric (also known as turmeric or saffron root), a spice commonly used in Indian and other Asian cuisines. It is a natural yellow dye that is safe to eat and can be used as a food coloring. Curcumin has attracted a lot of attention\u2026","rel":"","context":"In &quot;Micronutrients&quot;","block_context":{"text":"Micronutrients","link":"https:\/\/biocoach.health\/en\/category\/micronutrients\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0177.png?fit=1024%2C1024&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0177.png?fit=1024%2C1024&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0177.png?fit=1024%2C1024&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/biocoach.health\/wp-content\/uploads\/2024\/06\/IMG_0177.png?fit=1024%2C1024&ssl=1&resize=700%2C400 2x"},"classes":[]}],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/biocoach.health\/en\/wp-json\/wp\/v2\/posts\/1087665","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biocoach.health\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biocoach.health\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biocoach.health\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/biocoach.health\/en\/wp-json\/wp\/v2\/comments?post=1087665"}],"version-history":[{"count":1,"href":"https:\/\/biocoach.health\/en\/wp-json\/wp\/v2\/posts\/1087665\/revisions"}],"predecessor-version":[{"id":1087666,"href":"https:\/\/biocoach.health\/en\/wp-json\/wp\/v2\/posts\/1087665\/revisions\/1087666"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biocoach.health\/en\/wp-json\/wp\/v2\/media\/1087660"}],"wp:attachment":[{"href":"https:\/\/biocoach.health\/en\/wp-json\/wp\/v2\/media?parent=1087665"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biocoach.health\/en\/wp-json\/wp\/v2\/categories?post=1087665"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biocoach.health\/en\/wp-json\/wp\/v2\/tags?post=1087665"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}